Free Protoporphyrin in Red Blood Cells in Lead Poisoning
نویسندگان
چکیده
منابع مشابه
EFFECT OF CHRONIC LEAD POISONING ON ERYTHROCYTE PROTOPORPHYRIN IN RATS
Research has shown that exposure to lead may have adverse effects at different blood lead concentrations. Lead inhibits at least two enzymes that are essential for the formation of heme, and because of the interaction of lead with these enzymes, no iron is inserted into protoporphyrin. Therefore the concentration of protoporphyrin increases in erythrocytes. The concentration of lead was mea...
متن کاملeffect of chronic lead poisoning on erythrocyte protoporphyrin in rats
research has shown that exposure to lead may have adverse effects at different blood lead concentrations. lead inhibits at least two enzymes that are essential for the formation of heme, and because of the interaction of lead with these enzymes, no iron is inserted into protoporphyrin. therefore the concentration of protoporphyrin increases in erythrocytes. the concentration of lead was measure...
متن کاملFree erythrocyte protoporphyrin and zinc protoporphyrin measurements compared as primary screening methods for detection of lead poisoning.
We compared two commonly used primary screening methods (FEP and ZnP) for detecting Pb poisoning in children, used according to three major protocols. The results showed that FEP and ZnP values were comparable for only 36% of the children examined; 54% had FEP greater than ZnP and 10% had ZnP greater than FEP. One would identify approximately twice as many children with Pb greater than 300 micr...
متن کاملLead poisoning with low blood lead levels.
LANGE, K., WACHSTEIN, M., WASSERMAN, E., ALPTEKIN, F. & SLOBODY, L.B. (1963) The congenital nephrotic syndrome, an immune reaction? American Journal of Diseases of Children, 105, 338. MCDONALD, R., WIGGELINKHUIZEN, J. & KASHULA, R. (1971) The nephrotic syndrome in very young infants. American Journal of Diseases of Children, 122, 507. NORIo, R. (1966) Heredity in the congenital nephrotic syndro...
متن کاملEffect of bias in hematofluorometer measurements of protoporphyrin in screening programs for lead poisoning.
Values for erythrocyte protoporphyrin (EP), measured in our laboratory after extraction with ethyl acetate-acetic acid, were compared with hematofluorometer measurements made in 21 other laboratories. We found that: (a) for samples of patients' blood, hematofluorometer results were 11 to 28% lower than the extraction-based values, depending on the concentration of EP and the mathematical model ...
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ژورنال
عنوان ژورنال: Sangyo Igaku
سال: 1965
ISSN: 0047-1879,1881-1302
DOI: 10.1539/joh1959.7.4_278_1